Friday, April 24, 2020

Music Friday: Trumpeter Herb Alpert Teams Up With Janet Jackson in 1987’s ‘Diamonds’

Welcome to Music Friday when we bring you memorable songs with jewelry, gemstones or precious metals in the title or lyrics. Back in 1987, legendary jazz trumpeter Herb Alpert reinvigorated his career and climbed back to the top of the charts by collaborating with a 21-year-old Janet Jackson on a song called “Diamonds.”

Borrowing from "Diamonds Are a Girl's Best Friend” — the song famously performed by Marilyn Monroe in the 1953 film, Gentlemen Prefer Blondes — the Alpert/Jackson tune delivers the clear message that when a guy is serious about a girl, he needs to give her a tangible reminder of how much he cares. Specifically, Jackson wants something she can see — something on her finger that “shines so brightly.”

Jackson sings, “Don't you know / Diamonds are a girl's best / Best friend / When you go / They stay with me until the end.”

Herb Alpert & the Tijuana Brass had been one of the most successful acts of the 1960s, but faded from view by the end of the 1970s. With the 1987 release of his album Keep Your Eye on Me and the accompanying music video for “Diamonds,” the 52-year-old Alpert was back in the spotlight.

The video takes place at "Bucky's" nightclub, where the DJ is spinning “Diamonds” for an excited crowd and Alpert — trumpet in hand — gets into the act by playing live.

"Diamonds" charted in nine countries, including a #5 spot on the U.S. Billboard Hot 100 and a #4 position on the Canadian Singles chart. Jackson performed the song during her 2011 tour, "Number Ones: Up Close and Personal."

Born in Los Angeles in 1935, Alpert began trumpet lessons at the age of eight. After graduating high school in 1952, he joined the U.S. Army and played the trumpet at military ceremonies. While attending the University of Southern California in the mid-1950s, he was a member of the USC Trojan Marching Band.

In 1957, Alpert decided to pursue a career in music. He set up a recording studio in his garage and adopted a trumpet style inspired by the mariachi bands of Tijuana, Mexico.

The artist and his band, Herb Alpert & the Tijuana Brass, are credited with 14 Top 40 singles, 14 platinum albums and more than 72 million records sold. Alpert has won nine Grammy awards and is the only artist to have a #1 instrumental and a #1 vocal single. He is also the co-founder of A&M Records.

Please check out Alpert doing what he does best in the “Diamonds” music video. The lyrics are below if you’d like to sing along…

"Diamonds"
Written by Jimmy Jam and Terry Lewis. Performed by Herb Alpert, featuring Janet Jackson and Lisa Keith.

You told me you love me
You told me you care

But when I'm around you
It's like I'm not there
I need a reminder
Something I can see

Something on my finger shines so brightly

Don't you know
Diamonds are a girl's best friend

When you go
They stay with me until the end

Don't you know
Diamonds are a girl's best
Best friend

When you go
They stay with me until the end

Don't want your money
Don't want your key
Diamonds - love don't come for free

Don't want your money
Don't want your key
Diamonds - love don't come for free

They say you need some roses
But roses do die

You gave me some candy
It melted
Nice try
I'm not that demanding
I have simple taste
I just want a token that can't go to waste - Diamonds

Don't want your money
Don't want your key
Diamonds - love don't come for free

Don't want your money
Don't want your key
Diamonds - love don't come for free

Don't you know
Diamonds are a girl's best friend

When you go
They stay with me until the end

Don't you know
Diamonds are a girl's best
Best friend

When you go
They stay with me until the end

Don't want your money
Don't want your key
Diamonds - love don't come for free

Don't want your money
Don't want your key
Diamonds - love don't come for free

Don't want your money
Don't want your key
Diamonds - love don't come for free

Credit: Image by General Artists Corporation (GAC)/A&M Records (management and record companies) / Public domain.

Wednesday, April 22, 2020

Gold-Infused Drug Inhibits Spread of Coronavirus, Say Georgia State Researchers

Auranofin, a gold-infused drug originally developed in 1985 and approved by the FDA to treat rheumatoid arthritis, is effective at inhibiting the spread of the novel coronavirus, according to researchers at Georgia State University.

In the preliminary study, human cells infected with the virus were treated with Auranofin, and within 48 hours of treatment, the amount of virus within the cells dropped by 95 percent. Treatment also resulted in significant reduction of coronavirus-induced inflammation.

Like all viruses, SARS-CoV-2 (the virus that causes the disease COVID-19) cannot reproduce on its own. Instead it uses host cell proteins to manufacture copies of itself.

“Effective drugs need to interfere with this replication process, shutting down the virus’s ability to proliferate inside the host,” said Hussin Rothan, a post-doctoral researcher at Georgia State and co-author of the study.

Because the drug has already been approved by the U.S. Food & Drug Administration, it could potentially be fast-tracked to patients in need.

“Drug repurposing is the fastest way to get a treatment for SARS-CoV-2 because it’s already been established that these medicines are safe to use in humans,” said Mukesh Kumar, lead author of the study and assistant professor of biology.

Auranofin is a chemical compound containing particles of gold, an element known to have anti-inflammatory properties for nearly a century.

The Georgia State University researchers explained that Auranofin also dramatically reduced the expression of cytokines — signaling proteins that draw immune cells to the site of infection— caused by SARS-CoV-2. Normally, the immune system works by fighting off invading pathogens and repairing damage to the body’s tissues.

But many coronavirus-infected patients who die do so because of something called a “cytokine storm,” in which the body’s immune response spirals out of control, killing healthy tissue and leading to organ failure.

According to Kumar, the research seems to indicate that the drug not only could inhibit the replication of SARS-CoV-2, mitigating the infection, but also reduce the associated lung damage that often leads to severe respiratory distress and even death.

Precious metal has been used in medicine since ancient times, and more recently, scientists have explored gold compounds as effective treatments for HIV, cancer, neurodegenerative disorders and parasitic and bacterial infections.

Kumar and his team plan to test the drug in animal models to learn more about how it affects infection and illness, and whether it is effective in treating the disease.

The researchers at Georgia State University have made their paper publicly available for the global research and healthcare community on the preprint website bioRxiv.

Credits: Hussin Rothan image courtesy of Georgia State University. Graphic by https://www.scientificanimations.com / CC BY-SA.

Monday, April 20, 2020

World’s Top Diamond Producer, Alrosa, Doubles Spending to Battle COVID-19

Alrosa, the world’s leading diamond producer in terms of carats, has more than doubled its spending to counter the spread of COVID-19 in and around its mining and administrative sites in Yakutia and Moscow. Alrosa announced last week that its initial outlay of 147 million rubles ($1.99 million) has been elevated to 308 million rubles ($4.15 million).

The funds will continue to be used to buy sanitizers, ventilators, medical equipment, medicines and personal protective gear for regional healthcare institutions, corporate healthcare facilities, operating sites and subsidiary offices.

Specifically, hospitals near its mining facilities in Mirny, Lensk and Aikhal will be getting 25 million rubles ($340,000) in financial aid to purchase antibiotics, antivirals and other medicines and materials. The Ministry of Health of Yakutia will be getting 28,800 COVID-19 test kits valued at 23 million rubles ($311,000).

Alrosa Medical Center is slated to get six mobile labs that are capable of running express testing for COVID-19, and 17 thermal imaging cameras will be installed at the company’s production and administrative sites. The cameras can identify workers with fevers.

In Moscow, Alrosa made its former administrative building available to be utilized by the authorities in their counter-pandemic efforts.

Alrosa's CEO Sergey Ivanov has led by example. On April 6, Ivanov sold half his shares in the company for 18.5 million rubles ($250,000), which he then donated to the coronavirus initiatives in Yakutia, the home of Alrosa’s main operations and headquarters.

Alrosa is the world leader in diamond mining, accounting for more than 25% in the global diamond production in terms of carats. Alrosa operates more than 20 diamond deposits located in the Republic of Sakha (Yakutia) and the Arkhangelsk Region of Russia.

Credit: Image courtesy of Alrosa.